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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable transcriptional regulatory protein WhiB7
CommentsML0639, len: 89 aa. Probable whiB7, WhiB-like regulatory protein, highly similar to Rv3197A whiB7, WhiB-like regulatory protein from M. tuberculosis (92 aa), fasta scores: opt: 441, E(): 1.5e-26, (69.318% identity in 88 aa overlap); and CAD95313|Mb3221c from M. bovis (92 aa). Shows similarity to members of the whiB-family of transcriptional regulators e.g. Q8GHG1 WhiB7 from Streptomyces coelicolor A3(2) (122 aa), fasta scores: opt: 316, E(): 9.6e-17, (56.522% identity in 69 aa overlap). Also similar to ML0382, ML0760, ML0804 and ML2307 from M. leprae. Previously sequenced as Q49765|U00016 (89 aa), Fasta scores: E(): 0, (100.0% identity in 89 aa overlap). Contains a match to Pfam entry PF02467; Whib.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS771723771992+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0639|whiB7
MLTLTIPKQTLPGLPCHADTSDLWFAETPADLECTKTLCANCPIRRPCLEAAMERAEPWGVWGGEIFDRGLIVSRKRPRGRPCNDVVVV
      
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