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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved ATP-binding protein ABC transporter
CommentsML0640c, len: 473 aa. Probable conserved ATP-binding protein ABC transporter, highly similar to O53343|AL123456|Rv3197 conserved ATP-binding protein ABC transporter from M. tuberculosis (447 aa), Fasta scores: E(): 0, (83.0% identity in 447 aa overlap); and CAD95312|Mb3220 from M. bovis (447 aa). Similar to other proteins (generally ABC transporters) e.g. Q9FCJ6 Hypothetical protein SCO5192 from Streptomyces coelicolor (469 aa), fasta scores: opt: 1252, E(): 3.3e-72, (46.222% identity in 450 aa overlap). Also similar to ML1898. Previously sequenced as Q49747|U00016 (267 aa), Fasta scores: E(): 0, (99.6% identity in 248 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS772069773490-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0640c|ML0640c
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRAVLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEADNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLELTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVFHYTRKWLQQISLDRSVSHIKTARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV
      
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