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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPossible conserved secreted protein
CommentsML0643, len: 340 aa. Possible conserved secreted protein, highly similar to O53340|AL123456|Rv3194c conserved hypothetical protein from M. tuberculosis (340 aa), Fasta scores: E(): 0, (80.3% identity in 340 aa overlap); and CAD95308|Mb3216c from M. bovis (340 aa). Similar to other bacterial hypothetical and putative secreted protein e.g. Q8NS96 Predicted secreted protein containing a PDZ domain from Corynebacterium glutamicum (Brevibacterium flavum) (350 aa), fasta scores: opt: 912, E(): 9.5e-49, (42.571% identity in 350 aa overlap); and Q9S3Y5|AF170560 sdrC, hypothetical protein from Streptomyces coelicolor (241 aa), Fasta scores: E(): 5.5e-18, (34.9% identity in 318 aa overlap). Contains a possible N-terminal signal sequence.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS776009777031+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0643|ML0643
VNRRILTLLVALVPILVFGVLLAVVTVPFVSLGPGPTFDTLGEVDGKQVVAIKGAHTHPTSGHLNMTTVSQRDDLTLGEALTLWLSGQEQLVPRDLIYPPGKSREDVDKVNYADFKQSEDSAAYAALGYLQYPSAVTVAKVTDPGQSVGKLKSGDAVDAVNGSPVANVEQFTGLLKKTKPGEVVTIDFRRKNEPPGVVQITLGANKDRDYGFLGVAVLDAPWAPFVVDFNLANVGGPSAGLMFSLAVVDKLTTGDLVGSTFVAGTGTISIDGKVGPIGGIAHKMAAARAAGATVFLVPAKNCYEARSDNRTGLRLVKVESLSQAVDALHAMTSGGQLPSC
      
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