Gene ML0644 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0644
Gene length2952 bp
IdentifierML0644
Location 777177 bp
Protein summary information
Molecular mass107525.0 Da
Isoelectric point9.6
Protein length984 amino acids
Structural information
PFAMPF03699
Orthologues
M. tuberculosisRv3193c
Cross-references
UniProtQ9CCM6
Gene OntologyPlasma membrane, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved transmembrane protein
CommentsML0644, len: 983 aa. Probable conserved transmembrane protein, with hydrophobic N-terminal domain, highly similar to O53339|AL123456|Rv3193c conserved transmembrane protein from M. tuberculosis (992 aa), Fasta scores: E(): 0, (86.1% identity in 989 aa overlap); and CAD95307|Mb3215c from M. bovis (992 aa). Also similar to O53609|AL123456|Rv0064 putative membrane protein from M. tuberculosis (979 aa), Fasta scores: E(): 5.3e-175, (49.3% identity in 984 aa overlap) and to other bacterial hypothetical membrane proteins. Previously sequenced as O32904|Z98271 (277 aa), Fasta scores: E(): 0, (100.0% identity in 277 aa overlap). Contains hydrophobic, possible membrane-spanning regions.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS777177780128+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0644|ML0644
VGMRPAARMPKLTRRSRTLIMVALGVIVLLLAGPRLVDAYVEWLWFGELGYRSVFSTVLVTRVVVFLVAGLVVGGIVFAGLAVAYRTRPVFVPSHDNDPVARYRAMALSRLRLIGVGIPAAIGLLAGIIAQSYWVRIQLFLHGDNFGIRDPQFGKDLGFYAFELPFYRLVLSYVFVAVFLAFVVNLLAHYIFGGIRLSGRTGALSRLARLQLVSLVGVLVLLKAVAYWLDRYELLSRTRSSKPFTGAGYTDINAVQPAKLILIAIALICAAAVFSAITLRDFRIPAIGLVLLMLSSLIVGTGWPLIVEQLIAKPDAVRKESEYIRRSITATRHAYGLTEDVVTYRNYIGDAPAIAQQIATDHATTSNIRLLDPTIVSPAFTQFQRGKNFYYFPDQLSIDRYLDKKGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPQFLVNVVGNGTVVSEGPARLDQPRVYFGPVISNTSADYAIVGKNGDDREYDYETNTDTKRYTYAGSGGVPIGSWLSRSVFAAKFAERNFLFSSVIGSNSKILFNRDPAQRVEAVAPWLTTDSSVYPAIVNKRLVWIIDGYTTLDNYPYSERTSLSSATADSTEVAFNRLAPDKRVAYIRNSVKATVDAYDGAVTLYQQDEYDPVLKVWMKVFPGTVRPKGDITPELAEHLRYPEDLFKVQRMLLAKYHVNDPGTFFNTSDFWDVPLDPNPTASSYQPPYYIVAKNILKNDRSASYQLTSAMNRFKQDFLAAYISASSDPETYGKITVLTIPGNVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVAQGGLLYVEPVYASPGVSDAASSYPRLIRVAMMYNDKIGYGPTVGDALTGLFGPGAASAATGIEPTEAVPPKSPAGSSTPPIAVVPSAPDGSVALSAAKAAALQEIQAVIGAAREAQKKGDFVAYGSALQRLDDAITKFNSTK
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