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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable acyl-CoA dehydrogenase FadE23
CommentsML0660c, len: 400 aa. Probable fadE23, acyl-CoA dehydrogenase (1.3.99.-), highly similar to P95186|AL123456|Rv3140 fadE23, probable acyl-CoA dehydrogenase from M. tuberculosis (401 aa), Fasta scores: E(): 0, (89.5% identity in 401 aa overlap); and CAD95256|Mb3164 from M. bovis (401 aa). Similar to many e.g. Q9HUH1 Probable acyl-CoA dehydrogenase from Pseudomonas aeruginosa (402 aa), fasta scores: opt: 1550, E(): 4.7e-97, (60.0% identity in 400 aa overlap). Also similar to ML0737. Previously sequenced as O32891|Z98271 (400 aa), Fasta scores: E(): 0, (100.0% identity in 400 aa overlap). Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase. COULD BELONG TO THE ACYL-CoA DEHYDROGENASES FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS796048797250-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0660c|fadE23
MAINLELSRKLQAVIVKTHQGAAELMRPIARKYDLKEHTYPVELDTLFNLFAGAAESFAFAGADALGDEDNKDENHNGANMAALLQTLEACWGDVAMLLSIPYQGLGNAAISAVATNKQLERLGKVWAAMAITEPGFGSDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGHAAIKSFIVPREHPGVTVERLEYKLGIRGSDTAAIRFDNVRIPKDNLLGNPEIEVGKGFSGVMETFDNTRPIVAAMAVGVGRAALEEIRKILTDAGIEICYDKPSHSQNAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAGRMASDVTLKAVELAGTAGYSEKALLEKWARDSKILDIFEGTQQIQQLVVARRLLGLSSSELK
      
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