Gene ML0666c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) |
| Comments | ML0666c, len: 456 aa. Probable fprA, NADPH:adrenodoxin oxidoreductase (NADPH-ferredoxin reductase) (EC 1.18.1.2), highly similar to O05783|AL123456|Rv3106 fprA, NADPH:adrenodoxin oxidoreductase from M. tuberculosis (456 aa), Fasta scores: E(): 0, (80.8% identity in 459 aa overlap); and CAD96820|Mb3133 from M. bovis (456 aa). Also similar to other adrenodoxin oxidoreductases e.g. Q9RX19 Putative NADPH:adrenodoxin oxidoreductase from Deinococcus radiodurans (479 aa), fasta scores: opt: 1302, E(): 2.6e-76, (46.799% identity in 453 aa overlap). Also similar to ML2134. Previously sequenced as O32886|Z98271 (456 aa), Fasta scores: E(): 0, (99.8% identity in 456 aa overlap). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 801977 | 803347 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0666c|fprA
LRPHHIHHIAIVGSGPSGFFAAASVLKAADASDEINVAVDMLEMLPTPWGLVRSGVAPDHPKIKSISKQFEKTAEDPRFRFFGNVIVGKHIEPAELAERYDAVIYAVGAQSDRALNIPGEDLPGSIAAVDFVGWYNAHPNFHERSPDLSGSRAVVIGNGNVALDVTRILITDPDVLAFTDIADHALESLRPRGIEEVVIVGRRGPLQTAFTTLELRELADIEGVDVLVDPAQLEGISDENAAAAGKTTRQNIKVLRDYTVRTPKPGHRRIVFRFLTSPIEIKGKGKVERIVLGQNELVTDDNGRVAAKDTGVREELPAQLIVRSIGYRGVPTPGLPFDDSSVTIPNTNGRVNGSRNEYVVGWIKRGPTGVIGTNKKDSQDTVDTLMENLAGANDTEKFGADHADRLAEWLAERQPKLVTSAHWQAIDRFERAAGEPHGRPRVKLPNLAELLRIGHG
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