Gene ML0667
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable peptide chain release factor 2 PrfB (RF-2) |
| Comments | ML0667, len: 374 aa. Probable prfB, peptide chain release factor 2, highly similar to RF2_MYCTU|O05782|Rv3105c prfB, peptide chain release factor 2 from M. tuberculosis (371 aa), Fasta scores: E(): 0, (90.1% identity in 372 aa overlap); and CAD96819|3132c from M. bovis (378 aa). Similar to many e.g. RF2_STRCO|Q53915 prfB, peptide chain release factor 2 from Streptomyces coelicolor (368 aa), Fasta scores: E(): 4.9e-99, (66.9% identity in 369 aa overlap). Also similar to ML1134. Previously sequenced as RF2_MYCLE|O32885 (374 aa), Fasta scores: E(): 0, (99.7% identity in 374 aa overlap). Contains Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain. Contains PS00745 Prokaryotic-type class I peptide chain release factors signature. BELONGS TO THE PROKARYOTIC AND MITOCHONDRIAL RELEASE FACTORS FAMILY. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 803527 | 804651 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0667|prfB
VEPDRQTDIAALDSTLTTVERVLDVEGLRTRIEKLEHEASDPKLWDDQVRAQRVTSELSHAQGELRRIEELRRRLDDLPVLYELAAEERAAAAASGMEAFAEADAELKALRVDIEATEVRTLLSGEYDEREALITIRSGAGGVDAADWAEMLMRMYIRWAEQHKYGVEVLDTSYAEEAGVKSATFAVHAPFAYGTLASEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVEITDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHVPTGLVVTCQNEKSQLQNKVSAMRVLQAKLLERKRLEERAELDALKGRGGSSWGNQIRSYVLHPYQMVKDLRNEYEVGNPTAVLDGDIDGFLEAGIRWRNRRDIS
Bibliography
No article yet recorded
