Gene ML0670
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | INVOLVED IN GROWTH (PRINCIPALLY DURING LOG PHASE CELLS). THOUGHT TO BE INVOLVED IN ACTIVE TRANSPORT OF SEPTATION COMPONENT ACROSS THE MEMBRANE. RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. IS CODED IN AN OPERON ESSENTIAL FOR CELL DIVISION. |
| Product | Putative cell division protein FtsX (SEPTATION COMPONENT-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER |
| Comments | ML0670, len: 297 aa. Putative ftsX, cell division protein, septation component transport integral membrane protein ABC transporter, highly similar to FTSX_MYCTU|P96293|Rv3101c Putative ftsX, cell division protein, septation component transport integral membrane protein ABC transporter from M. tuberculosis (297 aa), Fasta scores: E(): 0, (80.8% identity in 297 aa overlap); and CAD96815|Mb3128c from M. bovis (297 aa). Similar to many e.g. FTSX_BACSU|O34876 ftsX, cell division protein ftsX homolog from Bacillus subtilis (296 aa), Fasta scores: E(): 1.5e-14, (25.8% identity in 302 aa overlap). Previously sequenced as FTSX_MYCLE|O32882 (287 aa), Fasta scores: E(): 0, (99.7% identity in 287 aa overlap). Contains hydrophobic, possible membrane-spanning regions. BELONGS TO THE FTSX FAMILY. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 806611 | 807504 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0670|ftsX
VRFGFLLNEVVTGLRRNVTMTIAMILTTAISIGLFGGGLLVVRLADNSRSIYLDRVETQVFLTDDISANDLTCNTNLCKALRGKIEARDDVKSLRFLNRQDAYDDAIRKFPQYRDVAGKDSFPASFIIKLANPVQHKEFDAATQGQPGVLSVLNQKELIDRLFAVLDGLSDVAFVIALVQAIGAILLIANMVQVAAYTRRTEIGIMRLVGASRWYTQLPFLLEAMVAATVGAVIAIVGLLVARAMFLNNALNQFYQANLIARVDYADVLYVSPWLLLLGVALAALTGYATLRIYVRR
Bibliography
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