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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable homoserine o-acetyltransferase MetA
CommentsML0682c, len: 382 aa. Probable metA, homoserine o-acetyltransferase (EC 2.3.1.31), highly similar to O53391|AL123456|Rv3341 metA, homoserine o-acetyltransferase from M. tuberculosis (379 aa), Fasta scores: E(): 0, (85.0% identity in 380 aa overlap); and CAD95499|Mb3373 from M. bovis (379 aa). Similar to many e.g. Q8FRT0|METX_COREF Homoserine O-acetyltransferase from Corynebacterium efficiens (388 aa), fasta scores: E(): 2.9e-65, (49.086% identity in 383 aa overlap). Previously sequenced as O32874|Z98271 (382 aa), Fasta scores: E(): 0, (100.0% identity in 382 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. BELONGS TO THE AB HYDROLASE FAMILY, HTA SUBFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS817110818258-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0682c|metA
MTISKVPTQKLPAEGEVGLVDIGSLTTESGAVIDDVCIAVQRWGELSPTRDNVVMVLHALTGDSHITGPAGPGHPTPGWWDWIAGPGAPIDTNRWCAIATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVEADIAALAAMGITKVAAVVGGSMGGARALEWIIGHPDQVRAGLLLAVGVRATADQIGTQTTQIAAIKTDPNWQGGDYYETGRAPENGLTIARRFAHLTYRSEVELDTRFANNNQGNEDPATGGRYAVQSYLEHQGDKLLARFDAGSYVVLTETLNSHDVGRGRGGIGTALRGCPVPVVVGGITSDRLYPLRLQQELAEMLPGCTGLQVVDSTYGHDGFLVESEAVGKLIRQTLELADVGSKEDACSQ
      
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