Gene ML0686
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable tryptophanyl-tRNA synthetase TrpS (TRYPTOPHAN--TRNA LIGASE) (TRPRS) (TRYPTOPHAN TRANSLASE) |
| Comments | ML0686, len: 343 aa. Probable trpS, tryptophanyl-tRNA synthetase (EC 6.1.1.2), highly similar to SYW_MYCTU|O53386|Rv3336c trpS, tryptophanyl-tRNA synthetase from M. tuberculosis (336 aa), Fasta scores: E(): 0, (83.8% identity in 339 aa overlap); and CAD95489|Mb3369c from M. bovis (336 aa). Similar to many e.g. SYW_ECOLI|P00954 trpS, tryptophanyl tRNA synthetase from Escherichia coli (334 aa), Fasta scores: E(): 0, (49.6% identity in 335 aa overlap). Previously sequenced as SYW_MYCLE|Q49901 (343 aa), Fasta scores: E(): 0, (100.0% identity in 343 aa overlap). Contains Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 822127 | 823158 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0686|trpS
MSTATGFSRIFSGVQPTSDSLHLGNALGAITQWVALQYDHPDEYEAFFCVVDLHAITIAQDPETLWRRTLVTAAQYLALGIDPGRAVVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFKDKALRQGADSTTVGLFTYPVLQAADVLAYDTDLVPVGEDQRQHLELARDLAQRFNSRFPDTFVVPDMFIPKMAAKIYDLADPTSKMSKSASSDAGLINLLDDPALSVKKIRAAVTDSEREIRYDPEVKPGVSNLLNIQSAVTGVDVDTLVQRYVGHGYGDLKKDTAEAVVEFVSPIKDRVDELMADLTELEVVLAVGAQRAQDVAGKTMQRVYDRLGFLPQRG
Bibliography
No article yet recorded
