Gene ML0734c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0734c
Gene length687 bp
IdentifierML0734c
Location 875151 bp
Protein summary information
Molecular mass25515.3 Da
Isoelectric point8.84
Protein length229 amino acids
Structural information
PFAMPF04138
Orthologs
M. tuberculosis H37RvRv3277
M. lepromatosis Mx1-22AMLPM_0734
Cross-references
UniProtQ7AQF6
Gene OntologyPolysaccharide biosynthetic process, Transport, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved transmembrane protein
CommentsML0734c, len: 228 aa. Probable conserved transmembrane protein, highly similar to Rv3277|MTCY71.17|P96882|Z92771 Probable conserved transmembrane protein from Mycobacterium tuberculosis hypothetical (272 aa), fasta scores: E(): 4e-84, (84.6% identity in 228 aa); and CAD95397|Mb3305 from M. bovis (272 aa). Also similar to other membrane proteins e.g. Q82DA6 Putative integral membrane protein from Streptomyces avermitilis (162 aa), fasta scores: E(): 1.2e-08, (35.075% identity in 134 aa overlap). Previously sequenced as Q49673|U00012. Contains hydrophobic, possible membrane-spanning regions.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS875151875837-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0734c|ML0734c
VSFPDATITRLPTVLQPYAQRYHELIKFAIVGGTTFIIDSAIFYTLKLTILEPKPVTAKVVAGIVAVIASYVLNREWSFRDRGGRERHNEALLFFAFSGIGVLLSMAPLWFSSYVLQLRAPTVSLTVENLADFLSAYIIGNLLQMAFRFWAFRRWVFPDAFARNPEKTLESALTAGGIAEVFEDAIDGVFEDFGDALLRAWRNRSRRLDLSPASQLGDSSEPRVSKTS
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