Gene ML0747c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable metal cation-transporting P-type ATPase C CtpC |
| Comments | ML0747c, len: 725 aa. Probable ctpC, metal cation-transport ATPase P-type (EC 3.6.3.-), integral membrane protein, highly similar to Rv3270|MTCY71.10|CTPC_MYCTU|P96875 ctpC, metal cation-transport ATPase P-type from Mycobacterium tuberculosis (718 aa), fasta scores: E(): 0, (86.0% identity in 713 aa), and to P77894|CTPV_MYCTU Probable cation-transporting ATPase from M. tuberculosis (770 aa), fasta scores: E(): 2.9e-70, (36.970% identity in 779 aa overlap). Similar to other metal transporting ATPases e.g. Q8FUE3 Putative copper-transporting ATPase from Corynebacterium efficiens (578 aa), fasta scores: E(): 3.6e-72, (40.702% identity in 570 aa overlap). Contains hydrophobic, possible membrane-spanning region. Contains 2 Pfam matches to entry PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00154 E1-E2 ATPases phosphorylation site. Contains PS01229 Hypothetical cof family signature 2. BELONGS TO THE CATION TRANSPORT ATPASES FAMILY (E1-E2 ATPASES), SUBFAMILY IB. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 888794 | 890971 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0747c|ctpC
MTLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTTSRLVASGVTIFTGYPFLRGALRFGKTGTDALVSVATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRAISALLSGTQDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVDGEVIDGEAVVNQSAITGENLPVSVMAGSHVHAGSVVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAITLAITKDVRRTMTVLLIACPCAVGLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEERHISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLISLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGALSPVLAAVLHNASSVAVVANSSRLIRYRLD
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