Gene ML0756c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0756c
Gene length1668 bp
IdentifierML0756c
Location 897972 bp
Protein summary information
Molecular mass61121.1 Da
Isoelectric point9.17
Protein length556 amino acids
Orthologues
M. tuberculosisRv3263
Cross-references
UniProtQ9CCK4
Gene OntologyMethyltransferase activity, Nucleic acid binding, Methylation
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productprobable DNA methylase (MODIFICATION METHYLASE) (METHYLTRANSFERASE)
CommentsML0756c, len: 555 aa. Probable DNA methylase (EC 2.1.1.-), highly similar to Rv3263|MTCY71.03|P96868|Z92771 Probable DNA methylase from Mycobacterium tuberculosis (553 aa), fasta scores: E(): 8.1e-195, (81.9% identity in 541 aa); CAD95383| from M. bovis (553 aa). Similar to several e.g. MT57_ECOLI|P25240 modification methylase eco57IM from Escherichia coli (544 aa), fasta scores: E(): 7.4e-36, (31.4% identity in 525 aa). Contains PS00092 N-6 Adenine-specific DNA methylases signature.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS897972899639-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0756c|ML0756c
MVITYIGAAPDTCSMTTFAGKTAASADKVRGGYYTPAPVARFLARWVRQAGQKILEPSCGDGRILREIAALTTQAHGVELLAHEARKSRKFCSVDTENFFTWLSKTQVGSWDGVAGNPPYIRFGNWAADQRDPALELMRHVGLRPTKLTNAWVPFVVASTTLVRDGGRVGLVVPAELLQVTYAAQLREFLLSLYREIILVTFERLVFDGILQEVVLFCGVVGAGPAQIRTINLRDAESLNSLAESNLGVESAPALLHEKEKWTKYLLDPAQIRLLRKLKHANAMTRFGEVADVDVGIVTGRNSFFTFTDADAHALKLRKHCVPLVSRSTQLAGIVYDTNCRANDIAAKHRTWLLDAPHHPTDSALVTHIDAGKRAGVDKGYKCSIRKPWWSTPSLWIPDLFMLRQIHLAPRLTVNAAAATSTDTVHRVRLIADVDPTALAAVFHNSATFAFAEIMGRSYGGGILELEPREAEQLPIPPPAYASTELGQDIDLLLKANEIEKALDIVDRRVLIDGLGLSPDLVAQCRTAWASLRDRRTKRGSRVNISRRPFDSPPS
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