Gene ML0848
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSORTER |
| Comments | ML0848, len: 724 aa. Possible transmembrane ATP-binding protein ABC transporter. Similar to Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein Rv2326c or MTCY3G12.08 SW:YN26_MYCTU (P71886) (697 aa) fasta scores: E(): 0, 76.9% identity in 697 aa. Shares similar domains with many ABC-type transporters e.g. Streptomyces roseofulvus ATPase component of putative ABC transporter frnD TR:O68910 (EMBL:AF058302) (524 aa) fasta scores: E(): 8.4e-14, 31.5% identity in 495 aa and Synechococcus sp. nitrate transport ATP-binding protein NrtD nrtD SW:NRTD_SYNP7 (P38046) (274 aa) fasta scores: E(): 1.6e-12, 34.8% identity in 198 aa. Previously sequenced as TR:O32971 (EMBL:Z98741). Contains hydrophobic, possible membrane-spanning regions. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1005909 | 1008083 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0848|ML0848
MDLCIHRRMALLCQATRRCHRWKTQLGRCAAPDLAPGTGTIGKVTAHDPRHLHHRSGSLQPGELAQASVLAALCAVTAIVSVVVPFAAGLALLGTVPMGLLAYRYRFRVLMTAMVAAGVIAFLITGLGGFIAVVNSAYIGGLTGVVKRKGQGTLTVIALALFAGLAFGAANVVALVVLGRLRHLIFKAMTANVDGIAATLTWMHLPWVAVQLKRYFADGLQHWPWMLLGYFVITILVVSLIGWWVLSRVLERIRDIPDVHKLDAPSACNEDAPVGPVPVWLDKVRFRYPHAGQDALREVSLDLRVGEHVAVTGANGSGKTTLMLILAGREPTSGTVDRPGAVGLGKLGGTAVVLQHPESQVLGTRVADDVVWGLPPGTDVDVNRLLREVGLDAFAERDTGSLSGGELQRLALAAALAREPSLLIADEVTSMVDRQGRDALLGVLSGLTKRHPIALVHITHYNNEADTADRTINLSDSPDNAGMAETVAPPVSTVAVDHRPHAPVLELVGVGHEYGSGTPWAKAALHDISFVVRQGDGVLVYGSNGSGKSTLAWIMAGLMVPTTGACLIDGRPTHEHVGAVALSFQAARLQLMRSRVDLEVASAAGFSPRDEDRVAAALGVVGLDPALAKRRIDQLSGGQMRRVVLAGLLACSPRALILDEPLAGLDAVSQRGLLRLLEDLRCERGLTVVVTSHDFVGLEDVCPRTVHLRNGALESVSTTAGGTS
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