Gene ML0859c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelipB
Gene length708 bp
IdentifierML0859c
Location 1021413 bp
Protein summary information
Molecular mass25002.4 Da
Isoelectric point6.62
Protein length236 amino acids
Structural information
PFAMPF03099
Orthologues
M. tuberculosisRv2217
Cross-references
UniProtO32961
Gene OntologyCytoplasm, Lipoate biosynthetic process, Lipoyl(octanoyl) transferase activity, Cellular protein modification process, GO:0008415
Enzyme Classification2.3.1.181
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable lipoate biosynthesis protein B LipB
CommentsML0859c, len: 235 aa. Probable lipB, lipoate-protein ligase B (EC. 6.-.-.-). Similar to Mycobacterium tuberculosis lipoate-protein ligase B lipB or Rv2217 or MTCY190.28 SW:LIPB_MYCTU (Q10404) (230 aa) fasta scores: E(): 0, 78.4% identity in 218 aa. Similar to Escherichia coli lipoate-protein ligase B lipB SW:LIPB_ECOLI (P30976) (191 aa) blastp scores:: 84.1 bits, 55% identity in 163 aa. Previously sequenced as SW:LIPB_MYCLE (O32961). Contains Pfam match to entry PF02111 Lipoate_B, Lipoate-protein ligase B. Contains PS01313 Lipoate-protein ligase B signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10214131022120-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0859c|lipB
MDSIRSIPTAIDVRQLGTVDYHIAWQLQRDLADARVAGGPDTLLLLQHPPVYTAGRRTQPHERPNPSLHGVPVVETDRGGKITWHGPGQLVGYPIIGLAEPLDVVNYVRRLEEALIKVCAELGLDTSRVNGRSGIWVPGSAGQPARKIAAIGVRVSRATTMHGFALNCQCDLDAFHAIVPCGISDAGVTSLSAELGRTVAVNDVRSAIAEAVNDALDGWLALSWLSTPASVTSTL
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