Gene ML0864c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepepB
Gene length1575 bp
IdentifierML0864c
Location 1027289 bp
Protein summary information
Molecular mass54323.6 Da
Isoelectric point6.52
Protein length525 amino acids
Structural information
PFAMPF00883, PF02789
Orthologs
M. tuberculosis H37RvRv2213
M. lepromatosis Mx1-22AMLPM_0864
Cross-references
UniProtO32956
Gene OntologyCytoplasm, Manganese ion binding, Metalloexopeptidase activity, Proteolysis, Aminopeptidase activity
Enzyme Classification3.4.11.1
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable cytosol aminopeptidase PepB
CommentsML0864c, len: 524 aa. Probable pepB, cytosol aminopeptidase (EC 3.4.11.1). Similar to Mycobacterium tuberculosis probable cytosol aminopeptidase pepA or pepB or Rv2213 or MTCY190.24 SW:AMPA_MYCTU (Q10401) (515 aa) fasta scores: E(): 0, 83.0% identity in 522 aa. Similar to many e.g. Rickettsia prowazekii cytosol aminopeptidase pepA or rp142 SW:AMPA_RICPR (P27888) (500 aa) fasta scores: E(): 0, 39.1% identity in 384 aa. Previously sequenced as TR:O32956 (EMBL:Z98741). Contains Pfam match to entry PF00883 Peptidase_M17, Cytosol aminopeptidase family. Contains PS00631 Cytosol aminopeptidase signature. Belongs to peptidase family M17.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10272891028863-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0864c|pepB
LPVTTDPGYQGPSVHVAASLPKHDVSSSVLIVPVVSASDSDESEDRPGAVVAAAEPFLTAAAVAEIEAGLRALEATGGSDQVHRLVAPSLPVGSVLTVSLGKPRSEWPADTIRRAAGVAARSLGRAEVVITTLAELPGESGASICSAVVEGLMLGSYRFTDFRSRKTAPKDNGLRKITVLANAKDAKKQSAHGATVASAVATARDLVNTPPSHLFPAEFAKCAKTLGESAGLEVEVLDDKALQKAGYGGVIGVGQGSSRTPRLVRLIHQGSRLAKNPKNARKVALVGKGITFDTGGISIKPAASMHHMTSDMAGAAAVIATITLAAQLKLPIDVVATVPMAENMPSGTAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIVRACQDNPDYLIETSTLTGAQTVALGSRIPGVMGSDKFRDRVAKTSQQVGENGWPMPLPDELKDDLKSTVADLANVSGQRFAGMLVAGAFLREFVADGVDWAHIDIAGPAYNTDSPWGYTPKGATGVPTRTMFAMLEDIANHG
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