Gene ML0866 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameilvE
Gene length1107 bp
IdentifierML0866
Location 1030184 bp
Protein summary information
Molecular mass39715.0 Da
Isoelectric point4.89
Protein length369 amino acids
Structural information
PFAMPF01063
Orthologs
M. tuberculosis H37RvRv2210c
M. lepromatosis Mx1-22AMLPM_0866
Cross-references
UniProtO32954
Gene OntologyBranched-chain-amino-acid transaminase activity, Branched-chain amino acid biosynthetic process
Enzyme Classification2.6.1.42
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE BRANCHED-CHAIN AMINO ACID TRANSAMINASE ILVE
CommentsML0866, len: 368 aa. Probable ilvE, branched-chain amino acid aminotransferase (EC 2.6.1.42). Similar to Mycobacterium tuberculosis probable branched-chain amino acid aminotransferase ilvE or Rv2210c or MTCY190.21C SW:ILVE_MYCTU (Q10399) (368 aa) fasta scores: E(): 0, 87.2% identity in 368 aa. Similar to many e.g. Mus musculus branched-chain amino acid aminotransferase (cytosolic) bcat1 or eca39 SW:BCAT_MOUSE (P24288) (386 aa) fasta scores: E(): 0, 41.0% identity in 329 aa. Previously sequenced as SW:ILVE_MYCLE (O32954). Contains Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV. Contains PS00770 Aminotransferases class-IV signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10301841031290+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0866|ilvE
MTSGFLEFTVSLSAHPVTDAERESILAEPGFGKYHTDHMVSIDYIDGRGWHDARVIPYGPIQLDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPDANAARLRSSARRIAIPELPDELFIDSLCQLIAVDNAWVPRVGGEEALYLRPFIFATEPGLGVRPAKQYRYLLIASPVGAYFKGGINPVTVWVSMEYVRASPGGTGAAKFGGNYAASLLAQTEAAANGCDQVVWLDAVERRFVEEMGGMNIFFVLGSGGSARLVTPELSGSLLPGVTRASLLQLAIDAGFSVEERKIDIDEWQKKAAAGEITEVFACGTAAFITPVSRVKYGDTEFTIAGGAPGEVTMALRDTLTGIQRGTFADTHGWMARLG
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