Gene ML0873 (cbhK)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable adenosine kinase adk |
| Comments | ML0873, len: 324 aa. Probable adk, adenosine kinase (EC 2.7.1.20). Similar to Mycobacterium tuberculosis adk, adenosine kinase Rv2202c or MTCY190.13C SW:YM02_MYCTU (Q10391) (324 aa) fasta scores: E(): 0, 83.3% identity in 324 aa, and to Streptomyces coelicolor putative kinase SC6G10.31C TR:Q9X816 (EMBL:AL049497) (338 aa) fasta scores: E(): 0, 58.9% id in 319 aa. Shows weak similarity to known kinases e.g. Bacillus subtilis ribokinase rbsK SW:RBSK_BACSU (P36945; P96733) (293 aa) fasta scores: E(): 1.2e-07, 26.1% identity in 283 aa. Contains Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase. Contains PS00583 pfkB family of carbohydrate kinases signature 1. Belongs to the carbohydrate kinase pfkB family. Previously known as cbhK. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1036452 | 1037426 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0873|adk
VTIAVTGSIATDHLMRFPGRFSEQLLVDNLHKVSLSFLVDDLVIHRGGVAGNMAYAIGVLGGDVALIGAVGDDFADYRDWLQNHGVNCDSVLISKTAHTARFVCTTDLDMAQIGSFYTGAMSEARNIKLVDAIATIGTPELVIIGANDPAAMLGYTQECRKLGLAFAADPSQQLARLSGEEIRNLIDGATYLFTNDYEWDLLLSKTGWSEADVMAQIQLRVTTLGAKGVDLVEPDGTRVHVSVVPEAGQVDPTGVGDAFRAGFLTGRSAGLSLERSAQLGSLVAVLVLESTGTQQWGWDRDVAVARLAGAYGEEAAAEITVVLS
Bibliography
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