Gene ML0874c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameasnB
Gene length2034 bp
IdentifierML0874c
Location 1037609 bp
Protein summary information
Molecular mass75741.4 Da
Isoelectric point6.99
Protein length678 amino acids
Structural information
PFAMPF00310, PF00733
Orthologs
M. tuberculosis H37RvRv2201
M. lepromatosis Mx1-22AMLPM_0874
Cross-references
UniProtQ9CCF2
Gene OntologyAsparagine synthase (glutamine-hydrolyzing) activity, Asparagine biosynthetic process
Enzyme Classification6.3.5.4
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable asparagine synthetase [glutamine-hydrolyzing] AsnB
CommentsML0874c, len: 677 aa. Probable asnB, asparagine synthetase (EC 6.3.5.4). Similar to Mycobacterium tuberculosis putative asparagine synthetase [glutamine-hydrolyzing] Rv2201 or mtcy190.12 SW:ASNH_MYCTU (Q10374) (652 aa) fasta scores: E(): 0, 83.3% identity in 659 aa and to Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 1 asnB or asn SW:ASNB_BACSU (P54420; O34902) (632 aa) fasta scores: E(): 0, 49.0% id in 614 aa. Contains Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II. Contains Pfam match to entry PF00733 Asn_synthase, Asparagine synthase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10376091039642-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0874c|asnB
MDDRRLRTLPNEAYWIAVCGLLAFVVASARADSRGSGGTNNILQADHSMARAVHLMRHRGPDELSTWSDPDIDGFSGGVAFGFNRLSIIDIAHSHQPLRWGPPETPNRYILVFNGEIYNYLELRDELVIRHGAAFATDGDGESIVAGFHYWGTEILTRLRGMFAFALWDTIAHELFCARDPFGIKPLFMATGTNGTAVASEKKCLLELAEVIRFDTQIDTRALQHYTVLQYVPEPETLHRGVHRLESGCYARIRPEQLDPATTRYFVPQFAATPITSSTEQTRYGEITAVLADSVAKHMRADVTVGSFLSGGIDSTAIAALAIRHNPRLITFTTGFEHEGFSEIDVAAASAEAIGARHIVKVVTPNEFVAALPEIVWYLDEPIADPALVPLFFVAREARKHVKVVLSGEGADELFGGYRIYREPLSLKPFDYLPGPLRRSMGKVSKSLPEGMRGKNLLHRGSLTLEERYYGNARNFSEAQLQAVLPRFHTGWTHTDVTAAVYAESVGWDPVARMQHIDLFTWLRGDILAKADKMTMANSLELRVPFLDPEVFAVASRLPMQAKITRTTTKYALRRALESIVPAHVLHRPKLGFPVPIRHWLRAGELLEWAYALVNSSQAEHLVNLAAVHRMLDEHRGGISDHSRRLWTVLIFMLWHAIFIEHSVVPQISEPQYPVQP
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