Gene ML0879c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) |
| Comments | ML0879c, len: 551 aa. Probable qcrB, Ubiquinol-cytochrome C reductase cytochrome B subunit (cytB), integral membrane protein. Similar to Mycobacterium tuberculosis ubiquinol-cytochrome C reductase cytochrome B subunit qcrB or Rv2196 or MTCY190.07 SW:QCRB_MYCTU (Q10388) (549 aa) fasta scores: E(): 0, 92.5% identity in 548 aa and to Streptomyces lividans ubiquinol-cytochrome C reductase cytochrome b subunit qcrB SW:QCRB_STRLI (Q9ZFB6) (549 aa) fasta scores: E(): 0, 44.8% identity in 533 aa. N-terminal half is similar to some cytochomes e.g. Bacillus stearothermophilus menaquinol-cytochrome C reductase cytochrome B subunit qcrB SW:QCRB_BACST (Q45658) (224 aa) fasta scores: E(): 1.1e-13, 27.1% identity in 207 aa. Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00033 cytochrome_b_N, Cytochrome b(N-terminal)/b6/petB. BELONGS TO THE CYTOCHROME B FAMILY. CORRESPONDS TO THE AMINO END OF MITOCHONDRIAL CYTOCHROME B. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1043158 | 1044813 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0879c|qcrB
MSPKSVPDIGDVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEIALYSFIVLLLTGVYLTLFFDPSMTDVTYNGVYQPLRGVEMSRAYQSTLDISFEVRGGLFVRQIHHWAALMFTAAIMVHLARIFFTGAFRRPRETNWVIGSLLLILAMFEGYFGYSMPDDLLSGIGLRAALSSITLGIPVIGTWLHWALFGGDFPGTILIPRLYALHILLIPGVILALIGLHLALVWFQKHTQFPGPGRTEYNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGFLQINPIWNLGPYKPSQVSAGSQPDFYMMWTEGLARIWPAWEFYFWHHTIPAPVWVAVIMALVFVLLITYPFLEKRFTGDYAHHNLLQRPRDVPVRTSIGAMAITFYMVLTLAAMNDIIALKFHISLNATTWIGRIGMVILPLLVYFITYRWCIGLQRSDRAVLEHGIETGIIKRLPHGAYIELHQPLGPVDDHGHPIPLEYQGTAVPKRMNKLGSAGSPSSGSFLFADPVSEDAALREATHVAEQRALTALREHQDSIASSPNGERGKH
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