Gene ML0882c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namectaE
Gene length609 bp
IdentifierML0882c
Location 1046922 bp
Protein summary information
Molecular mass22345.0 Da
Isoelectric point9.48
Protein length203 amino acids
Structural information
PFAMPF00510
Orthologs
M. tuberculosis H37RvRv2193
M. lepromatosis Mx1-22AMLPM_0882
Cross-references
UniProtO69582
Gene OntologyIntegral to membrane, Mitochondrial electron transport, cytochrome c to oxygen, Plasma membrane, Cytochrome-c oxidase activity
Enzyme Classification1.9.3.1
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CYTOCHROME C OXIDASE (SUBUNIT III) CTAE
CommentsML0882c, len: 202 aa. Probable ctaE, cytochrome c oxidase polypeptide III (cox3) (EC 1.9.3.1)Similar to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III ctaE or Rv2193 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E(): 0, 90.1% identity in 203 aa. Similar to many e.g. Synechococcus vulcanus cytochrome C oxidase polypeptide III ctaE SW:COX3_SYNVU (P50677) (201 aa) fasta scores: E(): 1.2e-23, 39.0% identity in 200 aa. Previously sequenced as TR:O69582 (EMBL:AL022602). Contains hydrophobic, probable membrane-spanning regions. Contains Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III. Belongs to the cytochrome c oxidase subunit 3 family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10469221047530-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0882c|ctaE
VTSTVGTLGTAITSRVHSLNRPNMVSVGTVVWLSSELMFFAGLFAMYFTARAQAGGKWPPSTELNLYQAVPVTLVLIASSFTCQMGVFSAERGDVFGLRRWYVITLLMGLFFVLGQGYEYYHLITHGTTIPSSAYGSVFYLATGFHGLHVTGGLIAFIFLLARTTMSKFTPAQATASIVVSYYWHFVDIVWIALFTVIYFIR
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