Gene ML0883 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrpD
Gene length1101 bp
IdentifierML0883
Location 1047667 bp
Protein summary information
Molecular mass37675.7 Da
Isoelectric point5.63
Protein length367 amino acids
Structural information
PFAMPF00591, PF02885
Orthologs
M. tuberculosis H37RvRv2192c
M. lepromatosis Mx1-22AMLPM_0883
Cross-references
UniProtO69581
Gene OntologyTryptophan biosynthetic process, Anthranilate phosphoribosyltransferase activity
Enzyme Classification2.4.2.18
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable anthranilate phosphoribosyltransferase TrpD
CommentsML0883, len: 366 aa. Probable trpD, anthranilate phosphoribosyltransferase (EC 2.4.2.18). Similar to Mycobacterium tuberculosis anthranilate phosphoribosyltransferase trpD or Rv2192c or MTCY190.03C SW:TRPD_MYCTU (Q10382) (370 aa) fasta scores: E(): 0, 80.1% identity in 362 aa. Similar to many e.g. Streptomyces coelicolor anthranilate phosphoribosyltransferase 1 trpD1 or SC6G10.20C SW:TRD1_STRCO (O68608) (354 aa) fasta scores: E(): 0, 48.8% identity in 363 aa. Previously sequenced as SW:TRPD_MYCLE (O69581). Contains Pfam match to entry PF00591 Glycos_transf_3, glycosyl transferase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10476671048767+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0883|trpD
VVLSSQPPSSRSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPAQIAAFAVAMKMKVPTAAEVSELADVMLSHARKLPTEAICQDIGETVDIAGTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGVRIDLGPEQVANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILGPLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLAGAKGPVRDAVVLNAAGAIVAYAGLSSHAEWSPAWDDGLARASAAIDSGAAEQLLARWVRFSQQV
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