Gene ML0896
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible) |
| Comments | ML0896, len: 462 aa. Probable aroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (EC 4.1.2.15). Highly similar to many others e.g. Mycobacterium tuberculosis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase TR:O53512 (EMBL:AL021957) (462 aa), Fasta scores: E(): 0, 89.7% identity in 465 aa overlap; and similar to many plant DAHP synthetase family proteins e.g. Arabidopsis thaliana SW:AROF_ARATH (SW:P29976) (525 aa), Fasta scores: E(): 0, 49.0% identity in 441 aa overlap. Identical to the previously sequenced Mycobacterium leprae 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase TR:O69569 (EMBL:AL022602) (462 aa), Fasta scores: E(): 0, 100.0% identity in 462 aa overlap. Contains Pfam match to entry PF01474 DAHP_synth_2, Class-II DAHP synthetase family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1061590 | 1062978 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0896|aroG
MNWTVDIPIDQLPPLPADLRARLDAALAKPAAQQPSWPTDQAAAMRTVLESVPPVTVPSEIIRLQEQLALVANGKAFLLQGGDCAETFVDNTEPHIRSNVRTLLQMAVVLTYGASLPVVKVARIAGQYAKPRSADVDALGLKSYRGDMINGFAPDAAAREHDPSRLVRAYANSSAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALAGEIGRGLAFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLAGAPEGPDDGLQLYDLSAHTVWIGERTRQLDGAHVAFAEVIANPIGVKMGATMTPELAVEYVERLDPHNKPGRLTLVSRLGNNKVRDVLPPIVEKVKATGHQVIWQCDPMHGNTHESSTGYKTRHFDRVVDEVQGFFEVHRALGTYPGGIHVEITGEDVTECLGGAQDISDTDLAGRYETACDPRLNTQQSLELAFLVAEMLRD
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