Gene ML0911
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX |
| Comments | ML0911, len: 359 aa. Probable murX, phospho-N-acetylmuramoyl-pentappeptidetransferase (EC 2.7.8.13). Identical to the previously sequenced Mycobacterium leprae phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) SW:MRAY_MYCLE (SW:O69555) (359 aa), Fasta scores: E(): 0, 100.0% identity in 359 aa overlap(SW:O69555). Also highly similar to phospho-N-acetylmuramoyl-pentapeptide-transferases from Mycobacterium tuberculosis Rv2156c SW:MRAY_MYCTU (SW:O06221) (359 aa), Fasta scores: E(): 0, 91.1% identity in 359 aa overlap(SW:O06221) and Escherichia coli SW:MRAY_ECOLI (SW:P15876) (360 aa), Fasta scores: E(): 6.2e-29, 35.9% identity in 343 aa overlap(SW:P15876). Contains multiple possible membrane spanning hydrophobic domains and a possible N-terminal signal sequence. Contains Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1079143 | 1080222 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0911|murX
MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTPSMGGVAIVAGIWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFLDDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADLSYVREIATVTLAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTAAYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVGACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQILAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFYGEWLATIGA
Bibliography
No article yet recorded
