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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductFtsW-like protein FtsW
CommentsML0913, len: 534 aa. Probable ftsW, cell division protein. Identical to the previously sequenced Mycobacterium leprae cell division protein, FtsW, TR:O69553 (EMBL:AL022602) (534 aa), Fasta scores: E(): 0, 99.8% identity in 534 aa overlap. Also highly similar many other FtsW-family proteins involved in cell wall formation e.g. from Mycobacterium tuberculosis FtsW-like protein SW:FTWH_MYCTU (SW:O06223) (524 aa), Fasta scores: E(): 0, 76.5% identity in 528 aa overlap and Escherichia coli FtsW SW:FTSW_ECOLI (SW:P16457) (414 aa), Fasta scores: E(): 3.6e-31, 37.0% identity in 370 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein. Contains PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. Contains PS00041 Bacterial regulatory proteins, araC family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10817031083307+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0913|ftsW
VGNALGRDRGRGTGDNNSVQAATTVEAVEPGTATTGEVSEAEAKRAGSLRAGVRGPQTRFDAWLGRPMASFHLIIAVAGLLTALGLIMVLSASGVRSYGDDGSAWIIFGKQVLWTIIGLIGGYSSLWMSIRFIRRIAFFSYVITIILLVLVLIPGIGNLANGSRKWFVIAGFSMQPSELAKIAFVIWGAHLLAARRMERASLREMLIPLVPAAVIALGLIVAQPDLGQTVSLGIILLALLWYAGLPLRVFITSLLAVFIAGAILAMSAGYRSERVRSWMNPEADPQDTGYQARQAKFALAHGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIARRSADPFLRLLTATTTMWVLGQAFINIGYVIGVLPVTGLQLPFISAGGTSAAAILFMIGIMANAARHEPEAVAALRAGRDDKVNQLLRLPLPVPYLPPRVETFRDRKQVRPQPGKASVGRKPARKAPREPDRPLRPAFPRVADRLEHRSGQYRAGQLRAGQRYTPRVRVFEGQRYG
      
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