Gene ML0989 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0989
Gene length1554 bp
IdentifierML0989
Location 1155734 bp
Protein summary information
Molecular mass56090.4 Da
Isoelectric point6.91
Protein length518 amino acids
Structural information
PFAMPF00919, PF04055
Orthologs
M. tuberculosis H37RvRv2733c
M. lepromatosis Mx1-22AMLPM_0989
Cross-references
UniProtQ49842
Gene OntologyCytoplasm, Iron ion binding, Trna modification, Transferase activity, 4 iron, 4 sulfur cluster binding
Enzyme Classification2.-.-.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL ALANINE, ARGININE-RICH PROTEIN
CommentsML0989, len: 517 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein SW:YR33_MYCLE (Q49842) (516 aa), Fasta scores: E(): 0, 99.8% identity in 516 aa overlap. Also highly similar to many other proteins of undefined function belonging to the the Pfam UPF0004 family, including: Mycobacterium tuberculosis Rv2733c SW:YR33_MYCTU (O33238) (512 aa), Fasta scores: E(): 0, 80.4% identity in 509 aa overlap and Bacillus subtilis YMCB_BACSU. Contains Pfam match to entry PF00919 UPF0004, Uncharacterized protein family UPF0004. Contains PS01278 Uncharacterized protein family UPF0004 signature. Belongs to the UPF0004 family.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11557341157287+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0989|ML0989
VVTRDAGMADDAATGSTRTYQVRTYGCQMNVHDSERLAGLLEAAGYQRAADEADVGDADVVVFNTCAVRENADNRLYGNLSHLAPRKRNNPDMQIAVGGCLAQKDKHTVLSKAPWVDIVFGTHNLGSLPTLLDRARHNKVAQVEIVEALQHFPSSLPSARESDYAAWVSISVGCNNSCTFCIVPSLRGKEVDRSPADILAEVEALVADGVLEVTLLGQNVNAYGVSFADPALARNRGSFAELLRSCGSIDGLERVRFTSPHPAEFTYDVIEAMAQTPNVCPSLHMPLQSGSDRVLRAMRRSYRVERYLGIIGQVRAAMPHAAITTDLIVGFPGETEEDFAATLDVVRQVRFTAAFTFQYSKRPGTPAAELGGQLPKAVVQERYERLVELQEQICMEENRVLIGRIVELLVTTGEGRKDARTARRTGRARDGRLVHFALDTPWEAQVRPGDIITVMVTEAAPHHLIADAGILTHRRTRAGDAHAARQCPRSIGLGQIPLGMPSVGQHSASIGSAGCAR
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