Gene ML1036c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namearsA
Gene length1290 bp
IdentifierML1036c
Location 1199240 bp
Protein summary information
Molecular mass46108.8 Da
Isoelectric point5.89
Protein length430 amino acids
Structural information
PFAMPF03600
Orthologs
M. tuberculosis H37RvRv2684
M. lepromatosis Mx1-22AMLPM_1036
Cross-references
UniProtP46838
Gene OntologyCitrate transmembrane transporter activity, Citrate transport, Integral to membrane, Plasma membrane, Arsenite transmembrane transporter activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSA
CommentsML1036c, len: 429 aa. Probable arsA, arsenic-transport integral membrane protein. Identical to the previously sequenced Mycobacterium leprae probable membrane transport protein SW:AG45_MYCLE (P46838) (429 aa), Fasta scores: E(): 0, 99.8% identity in 429 aa overlap. Also highly similar to Mycobacterium tuberculosis arsenic-transport integral membrane proteins Rv2684 YQ84_MYCTU (O07186) (429 aa), Fasta scores: E(): 0, 74.3% identity in 428 aa overlap and O07187|YQ85_MYCTU|Rv2685 (428 aa), fasta scores: E(): 3.3e-128, (74.239% identity in 427 aa overlap). Contains multiple possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11992401200529-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1036c|arsA
MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFYSHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTINAAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVIIVTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFIAHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTDVVNQLARATTTLTGGHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVASMPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS
Bibliography
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