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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPE FAMILY PROTEIN
CommentsML1053, len: 99 aa. Member of PE family protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:U15180) (99 aa), Fasta scores: E(): 0, 100.0% identity in 99 aa overlap. Also highly similar to the whole or just the N-terminus of many Mycobacterium tuberculosis PE-family proteins e.g. Rv1195 O05297 (111 aa), fasta scores: E(): 5.8e-13 (48.913% identity in 92 aa overlap) and TR:P71664 (EMBL:Z80108) (576 aa), Fasta scores: E(): 3.2e-10, 44.6% identity in 92 aa overlap. Also similar to ML1183c a possible paralogue of M. tuberculosis Rv1195.
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12203771220676+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1053|PE5
MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL
      
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