Gene ML1053 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE5
Gene length300 bp
IdentifierML1053
Location 1220377 bp
Protein summary information
Molecular mass10117.0 Da
Isoelectric point4.5
Protein length100 amino acids
Orthologs
M. tuberculosis H37RvRv1195
M. lepromatosis Mx1-22AMLPM_1053
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPE FAMILY PROTEIN
CommentsML1053, len: 99 aa. Member of PE family protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49943 (EMBL:U15180) (99 aa), Fasta scores: E(): 0, 100.0% identity in 99 aa overlap. Also highly similar to the whole or just the N-terminus of many Mycobacterium tuberculosis PE-family proteins e.g. Rv1195 O05297 (111 aa), fasta scores: E(): 5.8e-13 (48.913% identity in 92 aa overlap) and TR:P71664 (EMBL:Z80108) (576 aa), Fasta scores: E(): 3.2e-10, 44.6% identity in 92 aa overlap. Also similar to ML1183c a possible paralogue of M. tuberculosis Rv1195.
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12203771220676+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1053|PE5
MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL
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