Gene ML1059
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE DAPE |
| Comments | ML1059, len: 354 aa. Probable dapE, succinyl-diaminopimelate desuccinylase (EC 3.5.1.18). Identical to the previously sequenced Mycobacterium leprae TR:Q49949 (EMBL:U15180) (400 aa), Fasta scores: E(): 0, 100.0% identity in 354 aa overlap. Also highly similar to succinyl-diaminopimelate desuccinylases from Mycobacterium tuberculosis Rv1202 TR:O05303 (EMBL:Z93777) (354 aa), Fasta scores: E(): 0, 86.7% identity in 354 aa overlap and Corynebacterium glutamicum SW:DAPE_CORG (Q59284) (369 aa), Fasta scores: E(): 0, 56.3% identity in 359 aa overlap. Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40. Contains PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1223703 | 1224767 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1059|dapE
VLDLRGDPIELTAALVDIPSESRAEARIADAVETALRAQTAGFEIVRNGNAVLARTSLHRPARVLLAGHLDTVPVAGNLPSRCEKDVLHGCGTVDMKSGDAVFLHLAATVTEPVHDLTLMFYDCEEIDSAANGLVRIERELPEWLAADVAILGEPTGGYIEAGCQGTLRVVINAAGSRAHSARSWLGDNAIHKLGAVLDRLAAYRARTVDIDGCVYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPDRSVAAALRHVHDVFDGLDVQIEQTDAAVGALPGLSQPAAKALVEAADGQVRAKYGWTDVSRFAALGVPAVNYGPGDPNLAHRHDERVPVVQITAAVDMLRRYLGG
Bibliography
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