Gene ML1069
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE GLGC (ADP-glucose synthase) (ADP-glucose pyrophosphorylase) |
| Comments | ML1069, len: 404 aa. Probable glgC, glucose-1-phosphate adenylyltransferase (EC 2.7.7.27). Identical to the previously sequenced Mycobacterium leprae GlgC TR:Q49961 (EMBL:U15180) (419 aa), Fasta scores: E(): 0, 100.0% identity in 404 aa overlap. Also highly similar to many glucose-1-phosphate adenylyltransferases involved in glycogen biosynthesis e.g. from Mycobacterium tuberculosis Rv1213 SW:GLGC_MYCTU (O05314) (404 aa), Fasta scores: E(): 0, 92.6% identity in 404 aa overlap and Escherichia coli SW:GLGC_ECOLI (P00584) (430 aa), Fasta scores: E(): 0, 39.6% identity in 407 aa overlap. Contains Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase. Contains PS00809 ADP-glucose pyrophosphorylase signature 2. Contains PS00810 ADP-glucose pyrophosphorylase signature 3. Contains PS00808 ADP-glucose pyrophosphorylase signature 1. BELONGS TO THE BACTERIAL AND PLANTS GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1233352 | 1234566 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1069|glgC
MREVPQVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLVDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRFGPHWYTGSADAIYQSLNLIYDEDPDYLVVFGADHVYRMDPEQMLRFHIGSGAGATVAGIRVPRSDATAFGCIDADDSGRIRRFTEKPLKPPGTPDDPDKTFVSMGNYIFTTKVLVDAIRADADDDHSYHDMGGDILPRLVDGGMAAVYDFSQNEVPGATDWDRAYWRDVGTLDAFYDAHMDLVSLRPVFNLYNKRWPIRGESENLAPAKFVNGGSVQESVVGAGSIISAASVRNSVLSSNVVVDNGAIVEGSVIMPGARVGRGAVIRHAILDKNVVVGPGEMVGVDPERDREHFAISAGGVVVVGKGVWI
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