Gene ML1075c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE METHYLTRANSFERASE |
| Comments | ML1075c, len: 224 aa. Probable methyltransferase (EC 2.1.1.-). Previously sequenced Mycobacterium leprae TR:Q49969 (EMBL:U15180) (136 aa), Fasta scores: E(): 0, 100.0% identity in 136 aa overlap. Also highly similar to Mycobacterium tuberculosis possible methyltransferase Rv1220c TR:O33219 (EMBL:Z98260) (215 aa), Fasta scores: E(): 0, 85.5% identity in 214 aa overlap and Streptomyces mycarofaciens O-methyltransferase (EC 2.1.1.-) involved in the synthesis of the macrolide antibiotic midecamycin SW:MDMC_STRMY (Q00719) (221 aa), Fasta scores: E(): 2.3e-11, 30.5% identity in 223 aa overlap. Contains Pfam match to entry PF01596 Methyltransf_3, O-methyltransferase. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1238389 | 1239063 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1075c|ML1075c
MYGTGNNAVTPDQAAASRADSLFAHAEGSISEDAILASARERSEEIGARAVTPAVGALLSLLTKLSGGKAVAEVGTGAGVSGLWLLSGMSYDGVLTTIDIEPEYLRLAKQAFSEAGIGPSRTRLISGRGQDVLTRLADESYDLVFIDADPIDQPAYVVEGVRLLRSCGIIVVHRAALGGRAGDPAARDAEVTAVREAARLIAENERLTPALVPLGDGLLAAVRE
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