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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MRP-RELATED PROTEIN MRP
CommentsML1080c, len: 383 aa. Probable Mrp protein. Previously sequenced Mycobacterium leprae SW:MRP_MYCLE (P53382) (435 aa), Fasta scores: E(): 0, 100.0% identity in 383 aa overlap. Similar to many other MRP-family proteins, the function of which is unknown, e.g. Mycobacterium tuberculosis Rv1229c SW:MRP_MYCTU (O33225) (390 aa), Fasta scores: E(): 0, 82.1% identity in 374 aa overlap and Escherichia coli SW:MRP_ECOLI (P21590) (379 aa), Fasta scores: E(): 8.3e-30, 33.3% identity in 360 aa overlap. Contains Pfam match to entry PF01883 DUF59, Domain of unknown function. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS01215 Mrp family signature. BELONGS TO THE MRP/NBP35 FAMILY OF ATP-BINDING PROTEINS.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12437581244909-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1080c|mrp
MSRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTAAVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATAIAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMILPPIVHEVKVISIGQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMMPDGSRLQVFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIPIVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR
      
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