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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-BINDING LIPOPROTEIN LPQY
CommentsML1086, len: 468 aa. Probable lpqY, sugar-binding lipoprotein component of sugar transport system. Previously sequenced Mycobacterium leprae TR:Q49975 (EMBL:U15180) (469 aa), Fasta scores: E(): 0, 100.0% identity in 468 aa overlap. Also similar to many solute-binding transport proteins e.g. from Mycobacterium tuberculosis Rv1235 TR:O31095 (EMBL:AF028830) (468 aa), Fasta scores: E(): 0, 77.6% identity in 469 aa overlap and Escherichia coli SW:MALE_ECOLI (P02928) (396 aa), Fasta scores: E(): 0.00081, 23.4% identity in 295 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12483281249734+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1086|lpqY
VVSRRVHRAGTIILAALTLASVVLACGAGGDQLVISFYTPASEDATFTEVARRCTEQFDGRFAIQHVSLPRSPDEQRLQLARRLTGKDRSLDVMAMDVVWTAEFAEAGWTLPLSEDPAGLAEPDAIVDTLPGPLATATWKRKLYAAPVTTNTQLLWYRTDLVDQPPGDWNGMVAEAARLHAAGEPSWIAVQANQGEGLVVWFNTLLASAGGQVLSEDGRHVTLTDTPEHRAATVRALRIIKAVATVPGADPSITRTDEATARLAVEQGKAALEVNWPFVLASMLENAVKGGVAFLPLDRISELAGSINNVGTFVPNDEQFRIAYQATRNVFGFAPYPSVSRSEPAKVTIGGLNLAVASTSRHKAEAFEAVRCLRSEQSQQYLSIEGGLPAVRASLYSDPAFQDKYPMYTIIRQQLTDAAVRPVTPAYQAVSIRLSAALNPITDIDPEPMADRLAAQVQKAIDGKGLLP
      
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