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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC
CommentsML1089, len: 392 aa. Probable sugC, sugar-transport ATP-binding protein ABC transporter. Identical to the previously sequenced Mycobacterium leprae TR:Q49978 (EMBL:U15180) (392 aa), Fasta scores: E(): 0, 100.0% identity in 392 aa overlap. Also highly similar to many ABC-transport proteins including: Mycobacterium tuberculosis Rv1238 TR:O50454 (EMBL:AL021006) (393 aa), Fasta scores: E(): 0, 79.9% identity in 389 aa overlap and Agrobacterium radiobacter SW:LACK_AGRRD (Q01937) (363 aa), Fasta scores: E(): 0, 53.1% identity in 339 aa overlap lactose transport ATP-binding protein. Also similar to ML1424 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12515351252713+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1089|sugC
MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSAPTDA
      
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