Gene ML1094c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1094c
Gene length834 bp
IdentifierML1094c
Location 1259135 bp
Protein summary information
Molecular mass29335.3 Da
Isoelectric point9.86
Protein length278 amino acids
Structural information
PFAMPF00106
Orthologues
M. tuberculosisRv1245
Cross-references
UniProtQ9CC98
Gene OntologyBinding, Metabolic process, Oxidoreductase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
CommentsML1094c, len: 277 aa. Probable short-chain dehydrogenase/reductase (EC 1.-.-.-). Highly similar to several Mycobacterium tuberculosis putative oxidoreductases e.g. Rv1245c TR:O50460 (EMBL:AL021006) (276 aa), Fasta scores: E(): 0, 78.3% identity in 277 aa overlap. Also similar to many others including: Pseudomonas paucimobilis SW:LINX_PSEPA (P50198) (250 aa), Fasta scores: E(): 9.3e-17, 35.6% identity in 194 aa overlap 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12591351259968-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1094c|ML1094c
VEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR
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