Gene ML1113c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1113c
Gene length1890 bp
IdentifierML1113c
Location 1287740 bp
Protein summary information
Molecular mass68269.5 Da
Isoelectric point8.12
Protein length630 amino acids
Structural information
PFAMPF00005, PF00664
Orthologs
M. tuberculosis H37RvRv1272c
M. lepromatosis Mx1-22AMLPM_1113
Cross-references
UniProtQ9CC89
Gene OntologyAtpase activity, coupled to transmembrane movement of substances, Integral to membrane, Transport, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER
CommentsML1113c, len: 629 aa. Probable drugs-transport transmembrane ATP-binding protein ABC transporter. Highly similar to many proposed ABC transporter proteins including: Mycobacterium tuberculosis Rv1272c YC72_MYCTU (Q11047) (631 aa), Fasta scores: E(): 0, 75.4% identity in 623 aa overlap and Bacillus subtilis hypothetical ABC transporter ATP-binding protein SW:YFIC_BACSU (P54719) (604 aa), Fasta scores: E(): 0, 43.2% identity in 532 aa overlap. Also similar to the adjoining CDS ML1114. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12877401289629-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1113c|ML1113c
VTMATAPATRSCDFYCTIRRLLKQLVPQRRLSLTVITLGITGTAIGIIVPWVLGHTTDLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLSGMNLVPGQGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPHGQVPRINGRVEFQQVSFAYRTGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIAHHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA
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