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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ARGINYL-TRNA SYNTHETASE ARGS (ARGRS) (Arginine--tRNA ligase)
CommentsML1127, len: 550 aa. Probable argS, arginyl-tRNA synthase (EC 6.1.1.19). Identical to the previously sequenced Mycobacterium leprae arginyl-tRNA synthetase (arginine--tRNA ligase) SW:SYR_MYCLE (P45840) (550 aa), Fasta scores: E(): 0, 99.6% identity in 550 aa overlap. Also highly similar to many other arginyl-tRNA synthetases including: Mycobacterium tuberculosis Rv1292 SW:SYR_MYCTU (Q10609) (550 aa), Fasta scores: E(): 0, 84.9% identity in 550 aa overlap and Brevibacterium lactofermentum SW:SYR_BRELA (P41253) (550 aa), Fasta scores: E(): 0, 63.8% identity in 550 aa overlap. Contains Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases class I (R). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13165741318226+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1127|argS
VTPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIADVEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAGYQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAAVVREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKKSLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLIGQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTAAALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM
      
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