Gene ML1130
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE THREONINE SYNTHASE THRC |
| Comments | ML1130, len: 360 aa. Probable thrC, threonine synthase (EC 4.2.99.2). Identical to the previously sequenced Mycobacterium leprae probable threonine synthase SW:THRC_MYCLE (P45837;) (360 aa), Fasta scores: E(): 0, 99.7% identity in 360 aa overlap. Also highly similar to many other threonine synthases e.g. Mycobacterium tuberculosis Rv1295 SW:THRC_MYCTU (Q10610) (360 aa), Fasta scores: E(): 0, 94.9% identity in 354 aa overlap and Brevibacterium lactofermentum SW:THRC_BRELA (P09123) (352 aa), Fasta scores: E(): 0, 57.9% identity in 337 aa overlap. Contains Pfam match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent enzyme. Contains PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1320967 | 1322049 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1130|thrC
VSGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMISLVNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASAASIAGLLKAIDGGWVARGSTVVCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV
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