Gene ML1131
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE HOMOSERINE KINASE THRB |
| Comments | ML1131, len: 315 aa. Probable thrB, homoserine kinase (EC 2.7.1.39). Identical to the previously sequenced Mycobacterium leprae homoserine kinase (EC 2.7.1.39) SW:KHSE_MYCLE (P45836) (314 aa), Fasta scores: E(): 0, 99.7% identity in 314 aa overlap. Also highly similar to many other homoserine kinases including: Mycobacterium tuberculosis Rv1296 SW:KHSE_MYCTU (Q10603) (316 aa), Fasta scores: E(): 0, 82.0% identity in 311 aa overlap and Corynebacterium glutamicum SW:KHSE_CORGL (P08210) (308 aa), Fasta scores: E(): 0, 48.7% identity in 312 aa overlap. Contains Pfam match to entry PF00288 GHMP_kinases, GHMP kinases putative ATP-binding proteins. Contains PS00627 GHMP kinases putative ATP-binding domain. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1322117 | 1323064 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1131|thrB
LVTWMLPAGLVASAVVAASSANLGPGFDSIGLALSLCDEIVVETTDSGLVVVVDGEGADQVPMGPEHLVVRAVRRGLQAVGVSAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAVVNGFVAQIDSTPLSNAQLIQLASEFEGHPDNAAAAVLGGAVVSWVDRSYDQPDYCAVPLRLHPDIHLFAAIPEERSSTAESRVLLPARVSHDDARFNVSRAALLVVALTERPDLLMAATEDVLHQPHRASAMSASAEYLRLLRRHNVAATLSGAGPSLIALSTQSELPREAAEYGAANGFIIIKMTAGDEVCWRPEVTVPG
Bibliography
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