Gene ML1159 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1159
Gene length906 bp
IdentifierML1159
Location 1354283 bp
Protein summary information
Molecular mass31922.9 Da
Isoelectric point4.51
Protein length302 amino acids
Structural information
PFAMPF00085
Orthologues
M. tuberculosisRv1324
Cross-references
UniProtQ9CC76
Gene OntologyCell redox homeostasis
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE THIOREDOXIN
CommentsML1159, len: 301 aa. Possible thioredoxin. Previously sequenced Mycobacterium leprae TR:Q49716 (EMBL:U00014) (255 aa), Fasta scores: E(): 0, 100.0% identity in 217 aa overlap. Highly similar to Mycobacterium tuberculosis Rv1324 SW:YD24_MYCTU (Q10636) (304 aa), Fasta scores: E(): 0, 72.4% identity in 301 aa overlap. Also weakly similar in parts to several putative thioredoxins e.g. Alicyclobacillus acidocaldarius SW:THIO_ALIAC (P80579) (105 aa), Fasta scores: E(): 0.00045, 27.1% identity in 107 aa overlap.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13542831355188+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1159|ML1159
MAGAVDLSGLKQRARQKASTSDPASRATLGARGTGSSENTSVIEITEANFEDEVLVRSHEVPILVLVWSPRSDACVKLLETLSGLAVADSGTWLLATVNVDAVPRVAQIFGVDAVPTVVALAAGQPLSSFQGMQSVDQLRRWLDSLLSVTAGKLRGPTRSEDSAEIDPAIAQARQQLEAGDFLTAKQSYHAILDADPASVEAKAAIRQIDFLTRATAQHPDAVAVADAAPGDIAAAFAAADVQILNQDVTAAFERLIVLVRSTSGDERSSVRTRLIELFELFDPDDPNVIVGRRNLANALY
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