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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLUTAMATE RACEMASE MURI
CommentsML1172, len: 272 aa. Probable glutamate racemase (EC 5.1.1.3). Identical to the previously sequenced Mycobacterium leprae probable glutamate racemase (EC 5.1.1.3) SW:MURI_MYCLE (P46705) (272 aa), Fasta scores: E(): 0, 100.0% identity in 272 aa overlap. Also highly similar to many others involved in peptidoglycan biosynthesis including glutamate racemases from Mycobacterium tuberculosis Rv1338 SW:MURI_MYCTU (Q10626) (271 aa), Fasta scores: E(): 0, 88.9% identity in 271 aa overlap and Bacillus subtilis SW:MURI_BACSU (P94556) (272 aa), Fasta scores: E(): 0, 42.2% identity in 268 aa overlap. Contains Pfam match to entry PF01177 Asp_Glu_race, Aspartate / glutamate racemase. Contains PS00924 Aspartate and glutamate racemases signature 2. Contains PS00923 Aspartate and glutamate racemases signature 1.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13692081370026+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1172|murI
MSSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAICDDLVGRGVKILVIACNTASAACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEATGDPEAFIQLAARFLGPAVSGVQPARLHSRVR
      
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