Gene ML1217
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE) |
| Comments | ML1217, len: 385 aa. Probable bioF1, 8-amino-7-oxononanoate synthase (EC 2.3.1.47)Identical to the previously sequenced Mycobacterium leprae 8-amino-7-oxononanoate synthase (EC 2.3.1.47) SW:BIOF_MYCLE (P45487) (385 aa), Fasta scores: E(): 0, 100.0% identity in 385 aa overlap. Also highly similar to many othes e.g. Escherichia coli SW:BIOF_ECOLI (P12998) (384 aa), Fasta scores: E(): 0, 36.9% identity in 379 aa overlap, involved in biotin biosynthesis, and Mycobacterium tuberculosis Rv1569 SW:BIOF_MYCTU (O06621) (386 aa), Fasta scores: E(): 0, 80.1% identity in 381 aa overlap. Contains Pfam match to entry PF00222 aminotran_2, Aminotransferases class-II. Contains PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. BELONGS TO CLASS-II OF PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1439917 | 1441074 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1217|bioF
MKVPIETSPLAWLEAVEQQRRGAGLRRSLRPRSAVATELDLASNDYLGLSQHPDVIDGGVAALRVWGAGATGSRLVTGDTILHHELECELAEFVGACVGLLFSSGYAANLGAVVGLSGPGSLIVSDAYSHASLVDACRLSRARVVVTPHCDVDAVDTALRSCHEERAVVVTESVFSADGVLAPVSELHDVCRRHGALLLVDEAHGLGVRGGGRGLVYEVGLAGAPDVVITTTMSKALGSQGGAVLGSSAVRAHLINTARPFIFDTGLAPAAVGAARAALQILKAETWRPEAVLQHARTLAKICDLSELPQSAVVSVVLGDPEVALAAAIACLDAGVRVGCFRPPTVPAGTSRLRLTAHASLDSAKLEVARRVLTDVLGGCCVARR
Bibliography
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