Gene ML1222 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1222
Gene length597 bp
IdentifierML1222
Location 1443807 bp
Protein summary information
Molecular mass20601.1 Da
Isoelectric point7.57
Protein length199 amino acids
Orthologs
M. tuberculosis H37RvRv1591
M. lepromatosis Mx1-22AMLPM_1222
Cross-references
UniProtQ49626
Gene OntologyPlasma membrane, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED TRANSMEMBRANE PROTEIN
CommentsML1222, len: 198 aa. Conserved transmembrane protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49626 (EMBL:U00010) (198 aa), Fasta scores: E(): 0, 99.5% identity in 198 aa overlap. Highly similar to proteins of undefined function also found downstream of BioB orthologues in Mycobacterium tuberculosis Rv1591 TR:O06599 (EMBL:Z95586) (221 aa), Fasta scores: E(): 0, 63.8% identity in 188 aa overlap and Mycobacterium bovis BCG TR:O52590 (EMBL:AF041819) (193 aa), Fasta scores: E(): 0, 67.6% identity in 170 aa overlap.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14438071444403+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1222|ML1222
VTEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGHDYLGNESEHFFVAPCLMLGLLTVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAAVGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHGLLQVAATVLWPAGIAALVYAVLAAANGRDDLGGRLCSR
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