Gene ML1224c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1224c
Gene length720 bp
IdentifierML1224c
Location 1445950 bp
Protein summary information
Molecular mass26399.2 Da
Isoelectric point10.58
Protein length240 amino acids
Structural information
PFAMPF00293
Orthologs
M. tuberculosis H37RvRv1593c
M. lepromatosis Mx1-22AMLPM_1224
Cross-references
UniProtQ9CC66
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1224c, len: 239 aa. Conserved hypothetical protein. Previously sequenced Mycobacterium leprae hypothetical protein TR:Q49628 (EMBL:U00010) (286 aa), Fasta scores: E(): 0, 100.0% identity in 233 aa overlap. Also highly similar toseveral other proteins of unproven function including: Mycobacterium tuberculosis hypothetical protein Rv1593c TR:O06597 (EMBL:Z95586) (236 aa), Fasta scores: E(): 0, 85.7% identity in 238 aa overlap and Streptomyces coelicolor TR:Q9S233 (EMBL:AL109848) (239 aa), Fasta scores: E(): 1.1e-19, 38.2% identity in 191 aa overlap putative DNA hydrolase.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14459501446669-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1224c|ML1224c
MAYASTAHEVLAVVFQVRRVAEQVKGTPQKAKPQLSVLLWERSQDPQRGAWSLPGGRLRNDEDMTYSVRRQLAEKVDLRELAHLEQLAVFSEPARLPGTRMIASTFLGLVPSPATPELPPDTRWHPLNTLPSMAFDHGPMVTHARARLVAKMSYTNIGFALAPKEFALSTLRDIYGATLGYQVDATNLQRVLARRSVIIQTGTVAQSGRSGGRPAALYRFTDSQLRVTDEFAALRPPGN
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