Gene ML1230 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepapA3
Gene length1416 bp
IdentifierML1230
Location 1460739 bp
Protein summary information
Molecular mass52125.8 Da
Isoelectric point4.45
Protein length472 amino acids
Structural information
PFAMPF00668
Orthologs
M. tuberculosis H37RvRv1182
M. lepromatosis Mx1-22AMLPM_1230
Cross-references
UniProtQ49618
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3
CommentsML1230, len: 471 aa. Probable papA3, conserved polyketide synthase associated protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49618 (EMBL:U00010) (471 aa), Fasta scores: E(): 0, 99.8% identity in 471 aa overlap. Also highly similar to Mycobacterium tuberculosis proteins encoded downstream of several polyketide synthases e.g. Rv1182 TR:O50438 (EMBL:AL010186) (472 aa), Fasta scores: E(): 0, 75.8% identity in 471 aa overlap.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14607391462154+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1230|papA3
LQVGPLTLGTLLDWAPRAGKTISWQPTPATCEKVSQAPVSSVPVAYMQAQHIRGYVEQKAKGLDYSRLMIVSCDQLGQCDIRAINYIVNAHLRRHDTYRSWFEYTDEGEIIRHTLCDPADIEFVPIEHGQLSLAQIRELAVSTPDPLEWGCFQFGVIQAEEHFTFYASIDHVHVDAMIVGVTLMEFHMMYSALVSGAGPLELPEAGSYDDFCRRQHRFTSMLTAESPQIRSWTQFAEPNEGSFPDFPLPLGDPLEPTQADIVTITMLDEQQTDRFEAACTVAGARFVGGVLACCGLAEYELTGADTYYGLTPRDTRRIPTDVLTQGWFTGLVPITVPIAGSSFGDAARAAQNCFDTDVHLAEVPYDRVVELAPTVHKPRPNFPVINFLDAGTAPLSVLLTAGLDGLNIGVYSDGRYSYQMSIYVIRVEQETAVAVMFPDNPEAQESVARYLETLKSVFECVAESGHWRNVA
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