Gene ML1248 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1248
Gene length1671 bp
IdentifierML1248
Location 1489173 bp
Protein summary information
Molecular mass61645.7 Da
Isoelectric point5.12
Protein length557 amino acids
Structural information
PFAMPF00005
Orthologs
M. tuberculosis H37RvRv2477c
M. lepromatosis Mx1-22AMLPM_1248
Cross-references
UniProtQ7AQ80
Gene OntologyAtpase activity, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
CommentsML1248, len: 556 aa. Probable ATP binding protein ABC-transporter. Highly similar to many proposed ABC-transporter ATP-binding proteins including: Escherichia coli SW: YJJK_ECOLI and Mycobacterium tuberculosis Rv2477c TR:O53204 (EMBL:AL021246) (558 aa), Fasta scores: E(): 0, 92.3% identity in 557 aa overlap. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14891731490843+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1248|ML1248
MAEFIYTMKKVRKAHGDKVILDDVTLNFFPGAKIGVVGPNGAGKSSVLRIMAGMDKPNNGDAFLATGASVGILQQEPPLNEEKTVRGNVEEGLGDIKIKLDRFSEVAELMATDSSSELMEEMGRLQEELDHADAWDLDSQLEQAMDVLRCPPPDEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHLAGYAGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAERLTTQGRKDAKLQKRLTDELAWVRSGAKARQAKSKARLQRYEEMAAEAEKNRKFDFEEIQIPVGPRLGNMVVEVEHLDKGYGGRTLIKDLSFTLPRNGIVGIIGPNGVGKTTLFKTIVGLEQPDGGAVKIGETVKLSYVDQTRAGIDPKKIVWEVVSDGLDHIQVGQTEVSSRAYVSAFGFKGPDQQKLAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRWFLDRTCTHILAWEGDDEGKWFWFEGNFGAYEENKVERLGAEAARPHRVTHRKLTRD
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