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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable indole-3-glycerol phosphate synthase TrpC
CommentsML1271, len: 272 aa. Probable trpC, indole-3-glycerol phosphate synthase (EC 4.1.1.48). Highly similar to many indole-3-glycerol phosphate synthases involved in tryptophan biosynthesis e.g. Mycobacterium tuberculosis Rv1611 SW:TRPC_MYCTU (O06129) (272 aa), Fasta scores: E(): 0, 90.8% identity in 272 aa overlap and Streptomyces coelicolor SW:TRC1_STRCO (O68814) (269 aa), Fasta scores: E(): 0, 64.1% identity in 262 aa overlap. Contains Pfam match to entry PF00218 IGPS, Indole-3-glycerol phosphate synthases. Contains PS00614 Indole-3-glycerol phosphate synthase signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15145031515321+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1271|trpC
MCPATVLDSILKGVRADVAAREACISLSEIKAAAAAAPAPLDAMAALREPGIGVIAEVKRASPSVGSLATIADPAKLAQAYEDGGARIISVLTEERRFNGSLDDLDAVRAAVSVPVLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSALMSMLDRTESLGMIALVEVRTEQEADRALKAGAKVIGVNARDLMTLEVDRDCFSRIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVKSGDPRAAVADLVTAGTHPSCPKPAR
      
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