Gene ML1278 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametesB
Gene length894 bp
IdentifierML1278
Location 1521269 bp
Protein summary information
Molecular mass33270.6 Da
Isoelectric point6.97
Protein length298 amino acids
Structural information
PFAMPF02551
Orthologs
M. tuberculosis H37RvRv1618
M. lepromatosis Mx1-22AMLPM_1278
Cross-references
UniProtQ9CC48
Gene OntologyGO:0016291, Acyl-coa metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable acyl-CoA thioesterase II TesB
CommentsML1278, len: 297 aa. Probable acyl-CoA thioesterase II (EC 3.1.2.-). Highly similar to many acyl CoA thioesterases including: Escherichia coli SW:TESB_ECOLI (P23911) (285 aa), Fasta scores: E(): 5.6e-26, 32.1% identity in 287 aa overlap and Mycobacterium tuberculosis Rv1618 TR:O06135 (EMBL:Z95554) (300 aa), Fasta scores: E(): 0, 85.1% identity in 288 aa overlap.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15212691522162+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1278|tesB
VKRLWEKKTMSDFEELLAVLDLNRVADDLFIGSHPSKNPLRTFGGQLVAQSFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVVRLRDERRFANRRVDAIQDGMLLSSAMASYMSGGCGLEHAVEPPEAAEPHTRPPIGELLRGYEQIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVWVKALGALPNDPTLHTAAMLYSTDTTVLDSVITTHGLSWGFDRIFAVSANHSVWFHRQVNFDDWVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQEGVLKYFPASHR
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