Gene ML1289 (TB18.6) in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1289
Gene length531 bp
IdentifierML1289
Location 1537588 bp
Protein summary information
Molecular mass18553.8 Da
Isoelectric point5.39
Protein length177 amino acids
Structural information
PFAMPF01161
Orthologs
M. tuberculosis H37RvRv2140c
M. lepromatosis Mx1-22AMLPM_1289
Cross-references
UniProtQ9CC45
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN TB18.6 HOMOLOG
CommentsML1289, len: 176 aa. Conserved hypothetical protein. Similar to many proteins of undefined function including: Mycobacterium tuberculosis Rv2140c SW:YL40_MYCTU (O06235) (176 aa), Fasta scores: E(): 0, 86.3% identity in 175 aa overlap and Escherichia coli SW:YBCL_ECOLI (P77368) (183 aa), Fasta scores: E(): 1.1e-21, 45.3% identity in 161 aa overlap. Note this CDS contains a strong Pfam hit to the Eukaryotic phosphatidylethanolamine-binding protein motif. In Eukaryotes this motif is associated with the binding of hydrophobic ligands and nucleotides. Contains Pfam match to entry PF01161 PBP, Phosphatidylethanolamine-binding protein.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15375881538118+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1289|ML1289
MSLPPDPYAALPKLPSFHLTSDSITDGQPLATPQISGIMGAGGADVSPQLSWSGFPTETCSFAVTVYDPDAPTLSGFWHWAVANLPADVTELPAGVGNDGELPAGALTLINDAGMRRYIGAAPPPGHGVHRYYVAVHAVRVQKLNLSEDASPAFLGFNLFQHAIARAVIHGTYEQH
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