Gene ML1297 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1297
Gene length849 bp
IdentifierML1297
Location 1546120 bp
Protein summary information
Molecular mass30240.7 Da
Isoelectric point8.63
Protein length283 amino acids
Structural information
PFAMPF02673
Orthologs
M. tuberculosis H37RvRv2136c
M. lepromatosis Mx1-22AMLPM_1297
Cross-references
UniProtQ9CC42
Gene OntologyDephosphorylation, Integral to membrane, Peptidoglycan biosynthetic process, Plasma membrane, Regulation of cell shape, Response to antibiotic, Undecaprenyl-diphosphatase activity, GO:0007047
Enzyme Classification3.6.1.27
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPossible conserved transmembrane protein
CommentsML1297, len: 282 aa. Possible conserved transmembrane protein. Similar to Mycobacterium tuberculosis Rv2136c TR:O06239 (EMBL:Z95388) (276 aa), Fasta scores: E(): 0, 82.6% identity in 276 aa overlap. Also similar to several proposed undecaprenol kinases or bacitracin resistance proteins including: Escherichia coli SW:BACA_ECOLI (P31054) (273 aa), Fasta scores: E(): 3.7e-23, 34.0% identity in 265 aa overlap and Contains multiple possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15461201546968+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1297|ML1297
VTAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVAVLVYFGRDIVRILHAWCRGLTVTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRPLWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVGVAQTLALIPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVGLVAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT
Bibliography
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